Antibacterial activity of antibiotic-soaked polyvinylpyrrolidone-grafted silicon elastomer hydrocephalus shunts
نویسندگان
چکیده
منابع مشابه
Antibacterial activity of antibiotic-soaked polyvinylpyrrolidone-grafted silicon elastomer hydrocephalus shunts.
If shunts, inserted for the relief of hydrocephalus, are pretreated with antimicrobials, the incidence of shunt-associated infections (SAI) may be reduced. The duration of the antibacterial activity of shunts, made from conventional silicon elastomer (SE) or from SE grafted with the hydrogel polyvinylpyrrolidone (SEpvp), which had been soaked in various antibiotics, was assessed in vitro. For a...
متن کاملAntibiotic prophylaxis for patients with hydrocephalus shunts: a survey of pediatric dentistry and neurosurgery program directors.
A survey of antibiotic prophylaxis recommendations for patients with hydrocephalus shunts was sent to directors of advanced programs in pediatric dentistry and neurosurgery. Recommendations were sought for patients with ventriculoperitoneal (VP) or ventriculoatrial (VA) shunts who were to receive dental care. Most respondents believed that shunt infection (SI) was related infrequently to dental...
متن کاملHydrocephalus: new theories and new shunts?
The optimal and ideal management for any given clinical disorder should be fundamentally aimed at reversing or preventing the pathobiological mechanism underlying the disorder. For hydrocephalus, our current incomplete understanding of the pathophysiology is, in part, responsible for significant inadequacies of the current mainstay of treatment: the cerebrospinal fluid (CSF) shunt. The manageme...
متن کاملVentriculoperitoneal shunts to control hydrocephalus in adults
Hydrocephalus is a neurological disorder where there is an increased build up of cerebrospinal fluid (CSF) in the brain. One of the most prominent ways to treat this condition is the use of a ventriculoperitoneal (VP) shunt. Studies conducted are used to understand what the best treatment will be for certain patients with hydrocephalus. The overall goal of these studies is to determine how tech...
متن کاملEnhanced susceptibility to subcutaneous abscess formation and persistent infection around catheters is associated with sustained interleukin-1beta levels.
A persistent Staphylococcus epidermidis infection in mice around a subcutaneous polyvinylpyrrolidone-grafted silicon elastomer catheter (SEpvp) but not around a conventional silicon elastomer catheter was observed. With SEpvp pericatheter tissue, protracted and exaggerated interleukin-1beta (IL-1beta) production was found. Apparently, sustained levels of IL-1beta are associated with enhanced su...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2000
ISSN: 1460-2091,0305-7453
DOI: 10.1093/jac/45.2.221